Abiralieva 500 mg Tablet (Abiraterone Acetate): Global Export & Clinical Guide

Are you searching for a reliable international supplier for advanced prostate cancer treatments? PRIMECARE IMPEX, a premier pharmaceutical exporter from India, specializes in the bulk supply and global distribution of Abiralieva 500 mg Tablet.

We ensure that high-quality Indian generics reach the medical hubs of New York (USA), Bristol (UK), Sydney (Australia), and Riyadh (Saudi Arabia) with full regulatory compliance and supply chain integrity.

🏥 Product Overview: What is Abiralieva 500 mg?

Abiralieva 500 mg contains Abiraterone Acetate, a hormone-based therapy primarily used in the management of:

• Metastatic Castration-Resistant Prostate Cancer (mCRPC): For patients whose cancer has spread and no longer responds to surgical or medical treatments that lower testosterone.

• Metastatic High-Risk Castration-Sensitive Prostate Cancer (mHSPC): Often used in combination with androgen deprivation therapy (ADT).

⚙️ Mechanism of Action: The Science of Suppression

Abiraterone Acetate is a selective inhibitor of the CYP17 enzyme (17α-hydroxylase/C17,20-lyase).

1. Blocking Androgen Production: Unlike traditional therapies that only address testosterone from the testes, Abiralieva inhibits androgen production at three vital sources: the testes, the adrenal glands, and the prostate tumor itself.

2. Tumor Starvation: By drastically reducing testosterone levels to "castrate levels," the medication slows the growth and spread of hormone-sensitive prostate cancer cells.

💊 Dosage and Administration

• Standard Dose: Usually 1,000 mg (two 500 mg tablets) once daily.

• Important: Must be taken on an empty stomach (at least 1 hour before or 2 hours after food) as food significantly increases the absorption of the drug, which can lead to dangerous side effects.

• Combination: Typically administered alongside a corticosteroid (like Prednisone) to prevent mineralocorticoid exce.

⚠️ Side Effects & Safety Information

Commonly reported side effects include:

• Joint pain or swelling.

• Hypokalemia (low potassium levels).

• Fluid retention (edema) and Hypertension.

• Hot flashes and diarrhea.

• Increased liver enzymes (regular liver function tests are required).

❄️ Storage & Handling

• Temperature: Store at room temperature between 20°C to 25°C (68°F to 77°F).

• Protection: Keep the container tightly closed and protect it from light and moisture.

• Safety: Keep out of reach of children and pregnant women (who should not handle the tablets without gloves).

📄 Documentation & Export Excellence

PRIMECARE IMPEX provides a seamless export experience by handling:

• Certification: Provision of Certificates of Analysis (CoA) and technical dossiers.

• Compliance: Adherence to GMP standards.

• Logistics: Specialized pharmaceutical shipping for New York, Bristol, Sydney, and Riyadh, ensuring customs clearance and timely delivery.